| 摘要 |
Novel compounds of the formula <IMAGE> and therapeutically acceptable salts thereof particularly phosphate esters of 1-hydroxymethyl-2-organo-sulphonyl- benzimidazoles, are useful in therapy, particularly as inhibitors of gastric acid secretion and in the treatment of gastrointestinal inflammation, where D is a mono-, di-, or tri-phosphate group; X is SO or S; y is O or I; R<c> is (a) a mono or bicyclic aromatic heterocyclic structure which may be substituted or (b) a benzene or 5- or 6- membered heterocyclic ring linked via a C atom and containing as an alpha -substituent an N-containing group; A is a fused ring system; and R<1>, R<2>, R<3>, R<4> and R<5> are H or substituents. |
