发明名称 |
Derivatives of 1,1,2,2-tetramethyl-1,2-bis-(2-fluoro-4-hydroxyphenyl)-ethane |
摘要 |
Antitumor compounds corresponding to the following formula: <IMAGE> I in which the substituents R1 and R2 may be the same or different and represent hydrogen, an aminocarbonyl group, a C1-C6 alkylaminocarbonyl group, a di-C1-C6-alkylaminocarbonyl group, the group PO(OH)2, a C2-C8 alkanoyl group, a C2-C8 halogen alkanoyl group or a C3-C8 alkenoyl group, a process for their preparation, and their use in treating oestrogen-receptor-positive-tumors as well as the prostate carcinoma.
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申请公布号 |
US4745233(A) |
申请公布日期 |
1988.05.17 |
申请号 |
US19860871892 |
申请日期 |
1986.06.09 |
申请人 |
ASTA-WERKE AKTIENGESELLSCHAFT |
发明人 |
SCHONENBERGER, HELMUT;HARTMANN, ROLF W.;SCHNEIDER, MARTIN;SCHWARZ, WALTER;ENGEL, JURGEN |
分类号 |
C07F9/145;A61K31/055;A61K31/22;A61K31/27;A61K31/66;A61P35/00;C07C39/367;C07C67/00;C07C67/475;C07C69/95;C07C239/00;C07C269/00;C07F9/12;F16J15/00;(IPC1-7):C07C39/14;C07C125/04;C07C125/06 |
主分类号 |
C07F9/145 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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