摘要 |
NEW MATERIAL:KBS3-P1003 substance having the following physical and chemical properties. Elemental analysis (%), C 46.66, H 6.22, N 11.51, ash 4.36; ash point, 178-180 deg.C; appearance, white powder; solubility, soluble in water, methanol, ethanol and acetonitrile and insoluble in n-propyl alcohol, acetone, ethyl acetate, ether, chloroform, diethyl ether and petroleum ether; color reaction, negative to ninhydrin test; amino acid composition (ratio), Asp 3, Glu 1, Ser 1, pro 1, Tyr 1; containing 1mol of fatty acid having unknown structure per 1mol of the substance. USE:Antimycotic agent. PREPARATION:A microbial strain belonging to Bacillus genus and capable of producing KBS3-P1003 substance [e.g. Bacillus KB-S3 (FERM P-8986)] is cultured preferably under aerobic condition at 25-30 deg.C for 4 days. |