发明名称 |
Cephalosporin derivatives. |
摘要 |
<p>Compounds of the formula
<Chemistry id="chema01" num="0001"><Image id="ia01" he="24" wi="94" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>wherein R' is hydrogen or a conventional amino-protecting group, R<Sup>2</Sup> is a straight or branched chain alkyl, alkenyl or alkynyl containing from 1 to 4 carbon atoms, and
<Chemistry id="chema02" num="0002"><Image id="ia02" he="13" wi="18" file="IMGA0002.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>is a quaternary ammonio group as described herein, and nontoxic pharmaceutically acceptable salts, physiologically hydrolyzable esters and solvates thereof, as well as processes for their preparation, are disclosed. The compounds in which R' is hydrogen are potent antibacterial agents.</p> |
申请公布号 |
EP0121244(A2) |
申请公布日期 |
1984.10.10 |
申请号 |
EP19840103491 |
申请日期 |
1984.03.29 |
申请人 |
BRISTOL-MYERS COMPANY |
发明人 |
ABURAKI, SHIMPEI;NAITO, TAKAYUKI;OKUMURA, JUN;KAMACHI, HAJIME;NARITA, YUKIO |
分类号 |
A61K31/545;A61K31/546;A61P31/04;C07D277/20;C07D501/46;C07D513/04;C07D519/06;(IPC1-7):07D501/46;61K31/545 |
主分类号 |
A61K31/545 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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