摘要 |
<p>A waterbath comprising an open-topped tank or trough (10) containing an immersion heater (12), cooling coil (14) and thermostat temperature sensors (16a, 16b, 16c) has a programmable control system adapted to switch the heater and cooling coil on and off to provide rapid, automatic temperature cycling through a predetermined temperature/time profile comprising successive stages each characterised by a particular user-selected temperature and a dwell period during which the bath remains at that temperature. The apparatus is especially suitable for use in carrying out a polymerase chain reaction (PCR) process for amplifying nucleic acid sequences.</p> |