发明名称 A METHOD OF POTENTIATING CELL-MEDIATED IMMUNITY UTILIZING POLYAMINE DERIVATIVES
摘要 This invention relates to the use of a compound of the formula: RHN-Z-NH-(CH2)m-NH-Z-NHR or a pharmaceutically acceptable salt thereof, wherein m is an integer 3 to 12, Z is a saturated C2-C6 alkylene moiety of straight or branched chain configuration, each R group is independently H, a C1-C6 saturated or unsaturated hydrocarbyl, or -(CH2)x-(Ar)-X wherein X is H, C1-C6 alkoxy, halogen, C1-C4 alkyl, or -S(O)xR1, x is an integer 0, 1 or 2, and R1 is C1-C6 alkyl, for the preparation of a pharmaceutical composition useful for potentiating cell-mediated immunity.
申请公布号 ZA9003804(B) 申请公布日期 1991.03.27
申请号 ZA19900003804 申请日期 1990.05.17
申请人 MERRELL DOW PHARMACEUTICALS, INC. 发明人 TERRY LYNN BOWLIN;NELLIKUNJA JAYA PRAKASH
分类号 A61K31/13;A61K31/135;A61P31/12;A61P35/00;A61P37/04;C07C211/14;C07C211/22;C07C211/26 主分类号 A61K31/13
代理机构 代理人
主权项
地址
您可能感兴趣的专利