发明名称 QUINOLINE DERIVATIVES AS SYNTHETIC INTERMEDIATES
摘要 Trans-(+/-)-2-Amino (or substituted amino)-4-(permissibly-substituted)-6-C1-C3 alkyl (or allyl)-5,5a,-6,7,8,9,9a,10-octahydropyrimido[4,5-g]quinolines, the corresponding trans-(-) and trans-(+)-stereoisomers and salts thereof, useful in treating Parkinson's Syndrome, sexual dysfunction, depression, hypertension, and prolactin related diseases, and intermediates useful for the synthesis thereof, are disclosed. The products are prepared by condensing an appropriate ketone with the appropriately substituted guanidine.
申请公布号 AU8216887(A) 申请公布日期 1988.03.31
申请号 AU19870082168 申请日期 1987.12.07
申请人 ELI LILLY AND CO., 发明人 MARK MORTENSEN FOREMAN;CYNTHIA LYNN NICHOLS;EDMUND CARL KORNFELD;JOHN MEHNERT SCHAUS;DIANE LYNN HUSER;RICHARD NOLAN BOOHER;DAVID TAIWAI WONG
分类号 A61K31/505;A61P5/00;A61P9/12;A61P25/00;A61P25/20;A61P25/24;A61P25/26;C07D215/20;C07D471/04;C07D495/10;C07D495/20 主分类号 A61K31/505
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