发明名称 A METHOD FOR THE PROPHYLACTIC TREATMENT OF CATARACTS
摘要 The present invention is directed to a method for the prophylactic treatment of cataract. The method involves the administration of a compound of formula (I) wherein V, W and X are selected from the group consisting of hydro, hydroxyl, alkoxy, halo, an ester, an ether, a carboxylic acid group, a pharmaceutically acceptable salt of a carboxylic acid group, and -SR, in which R is hydrogen or an alkyl group, Y is selected from the group consisting of oxygen, sulfur, C(OH), and C=O, and Z is selected from the group consisting of hydro and C(O)OR1, wherein R1 is an alkyl, or an analogue or prodrug thereof or a pharmaceutically acceptable salt of any of the foregoing to an animal, such as a mammal, in particular a human, in an amount sufficient to treat cataracts prophylactically. The compound of Formula (I) is preferably genistein.
申请公布号 WO0037066(A2) 申请公布日期 2000.06.29
申请号 WO1999US30634 申请日期 1999.12.22
申请人 JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE 发明人 DE JUAN, EUGENE, JR.
分类号 A61K31/35;A61K31/352;A61K31/52;A61K45/06;(IPC1-7):A61K31/00 主分类号 A61K31/35
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