发明名称 |
APPARATUS AND METHODS FOR MINIMIZING CELLULAR ADHESION ON PERITONEAL INJECTION CATHETERS |
摘要 |
<p>The present invention is directed to a subcutaneous peritoneal injection catheter apparatus and methods which minimize catheter obstruction during use. The apparatus includes a receiving chamber or reservoir having a relatively small internal volume while employing a penetrable membrane and relatively enlarged target surface area. The reservoir is interconnected with the peritoneal cavity by a hollow stem. The penetrable membrane accommodates a hollow needle being inserted into the receiving reservoir and is configurated with a dome-like profile so that the membrane may also be depressed to expel insulin from the receiving reservoir into the peritoneal cavity in a direction generally toward the mesenteric peritoneal membrane. The portion of the apparatus which is in the peritoneal cavity is preferably constructed of, or coated with, a material which is capable of minimizing the adhesion of cells and the growth of bacteria on that portion of the apparatus. In a presently preferred embodiment of the subcutaneous peritoneal injection catheter, the portion of the catheter to be within the peritoneal cavity is constructed of a polyurethane material, and this polyurethane material is then coated with a solution of polyurethane and poly(ethylene glycol) in a suitable solvent.</p> |
申请公布号 |
CA1234030(A) |
申请公布日期 |
1988.03.15 |
申请号 |
CA19840467690 |
申请日期 |
1984.11.13 |
申请人 |
UNIVERSITY OF UTAH RESEARCH FOUNDATION |
发明人 |
GREGONIS, DONALD E.;STEPHEN, ROBERT L.;COLEMAN, DENNIS L.;HUNTER, STEPHEN K.;HANOVER, BARRY K.;HARROW, JEFFREY J. |
分类号 |
A61M5/00;(IPC1-7):A61M5/00 |
主分类号 |
A61M5/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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