| 摘要 |
1. A trans-4-substituted cyclohexylamine derivative of the formula see diagramm : EP0258853,P24,F2 where R**1 is the group CR**5 R**6 R**7 , in which R**5 , R**6 and R**7 are identical or different and are each hydrogen, branched or straight-chain, unsubstituted or hydroxyl-substituted C1 -C8 -alkyl, C1 -C6 -alkoxy, C1 -C6 -alkylthio or C3 -C6 -cycloalkyl, with the proviso that not more that one of the substituents R**5 , R**6 and R**7 may be hydrogen, or in which R**5 has one of the above meanings and R**6 and R**7 together with the included carbon atom form a three-membered to six-membered carbocyclic aliphatic ring, R**2 and R**3 are identical or different and are each hydrogen, C1 -C20 -alkyl, C2 -C4 -alkenyl or C3 - or C4 -alkynyl or C3 -C12 -cycloalkyl or C5 -C8 -cycloalkenyl, which in turn may be substituted by hydroxyl, C1 -C8 -alkoxy, C1 -C6 -alkylthio, C1 -C8 -alkyl, C2 -C4 -alkenyl, C3 - or C4 -alkynyl or unsubstituted or substituted C3 -C12 -cycloalkyl or by phenyl, naphthyl, phenoxy or naphthyloxy, which in turn may be unsubstituted or substituted by C1 -C8 -alkyl, C2 -C4 -alkenyl, C3 - or C4 -alkynyl or C3 -C6 -cycloalkyl or C5 -C8 -cycloalkyl, C2 -C8 -alkoxy, halogen or trifluoromethyl, with the proviso that the sum of the carbon atoms and hetero atoms (O, S and halogen) of R**2 and R**3 together is not less than 8, the radicals R**4 are identical or different substituents selected from the group consisting of hydrogen, C1 -C8 -alkyl, C3 -C8 -cycloalkyl and C1 -C8 -alkoxy, and m is 1 to 4, and the ~.~.~. bond is a single or a double bond, or a salt thereof, with the exception of a compound in which at one and the same time R**1 is tert-butyl, one of R**2 and R**3 is hydrogen and the other is unsubstituted C8 -C12 -alkyl, and R**4 is hydrogen. |
