| 发明名称 |
Prodrugs of antihypercholesterolemic compounds. |
| 摘要 |
<p>Prodrugs of 3-hydroxy-3-methylglutarylcoenzyme A (HMG-CoA) reductase inhibitors which are useful as antihypercholesterolemic agents and are represented by the following general structural formula (I): <CHEM> the amido ester moiety of which is in the L-configuration, and pharmaceutically acceptable salts thereof are disclosed.</p> |
| 申请公布号 |
EP0259086(A2) |
申请公布日期 |
1988.03.09 |
| 申请号 |
EP19870307500 |
申请日期 |
1987.08.25 |
| 申请人 |
MERCK & CO. INC. |
发明人 |
BALDWIN, JOHN J.;HALCZENKO, WASYL;HARTMAN, GEORGE;PITZENBERGER, STEVEN M. |
| 分类号 |
A61K31/415;C07D207/08;A61K31/195;A61K31/22;A61P3/06;A61P9/10;A61P43/00;C07C67/00;C07C231/00;C07C233/45;C07C235/26;C07C235/30;C07C313/00;C07C323/59;C07D209/14;C07D233/64;(IPC1-7):C07C103/737;C07C103/84;A61K31/16;A61K31/165 |
主分类号 |
A61K31/415 |
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