发明名称 |
Direct and simultaneous assays for antigens in clinical specimens by monoclonal antibody immunoblot, antibodies for use therein and corresponding hybridomas. |
摘要 |
<p>This invention relates to a diagnostic method of employing a monoclonal antibody in a Western immunoblot assay for detecting antigens in clinical specimens. This invention further provides a method of simultaneously detecting a variety of antigens in a single Western immunoblot assay by incorporating in said assay monoclonal antibodies to each antigen to be detected. Said method presents a differential diagnosis procedure employing a panel of monoclonal antibodies to antigens of various symptomatically related etiologic agents. This invention further relates to a murine IgG1 monoclonal antibody which binds to a protease sensitive, periodate insensitive epitope on Mycoplasma pneumoniae membrane polypeptide with an approximate molecular weight of 43K. It also specifically relates to a diagnostic method for detecting M. pneumoniae with said monoclonal antibody in clinical specimens.</p> |
申请公布号 |
EP0254384(A2) |
申请公布日期 |
1988.01.27 |
申请号 |
EP19870302688 |
申请日期 |
1987.03.27 |
申请人 |
CETUS CORPORATION |
发明人 |
COATES, STEPHEN R.;SAEED, FAWZIA A.;MADSEN, RANDALL D. |
分类号 |
C07K16/12;C12P21/08;G01N33/543 |
主分类号 |
C07K16/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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