PERFLUOROCHEMICALS, PROCESS FOR PREPARING THE SAME AND THEIR USE AS BLOOD SUBSTITUTES

摘要

A perfluorochemical which is useful as a blood substitute or perfusion medium has the formula, wherein RF is a perfluoroalkyl group, a perfluoro alkoxyalkyl group or a perfluoroalkyloxy group, X and X min are same as or different from each other and are a fluorine atom or a perfluoralkyl group, and Y is a perfluoroalkyloxy group or a perfluoro dialkylamino group, the total number of the carbon atoms contained in the perfluorochemical being an integer of from 8 to 11 inclusive. The perfluorochemical is prepared by perfluorinating the corresponding partially fluorinated compound which may have an unsaturated hydrocarbon moiety, with undiluted molecular fluorine in a stoichiometric excess in an inert solvent. For use as a blood substitute or perfusion media, the perfluorochemical may be incorporated in a stable emulsion.