The present invention is concerned with the formation of small particles of organic compounds whose solubility in water is independent of temperature and greater at a first pH than at a second pH. upon precipitation by pH change with or without a change in temperature, but in the presence of a surfactant mixture.
申请公布号
EP0130160(B1)
申请公布日期
1988.01.07
申请号
EP19840850176
申请日期
1984.06.12
申请人
THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION
发明人
FRANK, SYLVAN GERALD;BRODIN, ARNE FOLKE;CHEN, CHIH-MING JAMES;SHRIVASTAVA, RATNESH