发明名称 |
CYTOPHAGA-DERIVED IMMUNOPOTENTIATOR |
摘要 |
Substantially pigment-free gliding bacteria adjuvant (GBA) is isolated from medium in which Cytophaga strain GB-2 has been cultured by extraction with acetone to remove pigment, enzymatic digestion and filtration to remove residual protein and nucleic acids, and affinity chromatography to remove residual lipopolysaccharide. This pure form of GBA shows unexpectedly high specific immunopotentiating activity relative to crude GBA. |
申请公布号 |
WO8707897(A1) |
申请公布日期 |
1987.12.30 |
申请号 |
WO1987US01469 |
申请日期 |
1987.06.23 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
MISHELL, ROBERT;USINGER, WILLIAM |
分类号 |
A61K39/39;C12P19/04;(IPC1-7):C08B30/04;C07H1/00;A61K31/71;A61K39/00;A61K39/12 |
主分类号 |
A61K39/39 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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