| 摘要 |
PURPOSE:The titled application agent, consisting of an adhesive layer containing specific hollow fibers containing a specific drug in the hollow parts thereof and support and capable of reducing the amount of residual solvent with suppressed side effect. CONSTITUTION:An application agent, consisting of an adhesive layer containing hollow fibers containing a drug, e.g. nitric acid ester, guaiazulene, camphor, etc., having evaporation property in hollow fibers, e.g. polyester, woven, knitted, nonwoven fabrics, etc., having through-holes in the outer peripheral direction and a support for supporting the above-mentioned layer and obtained by adjusting the total amount of the residual solvent, e.g. ethyl acetate, etc., for dissolving the above-mentioned drug and/or adhesive to 0.5-50ppm based on the total formulation. In the process, the above-mentioned hollow fibers and the adhesive layer, prepared by previously reducing the amount of the residual solvent and containing no drug are united and heat-treated or without heat treatment to afford the aimed application agent. A release sheet may be formed on the adhesive layer and, as necessary, an absorption adjuvant, etc., may be contained.
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