| 摘要 |
<p>New Compound, 3 min ,4 min -dideoxy-3 min -fluorokanamycin B is now provided, which is useful as antibacterial agent. …<??>3 min ,4 min -Dideoxy-3 min -fluorokanamycin B is prepared by a process comprising halogenating an N,O-protected derivative of 3 min -deoxy-3 min -fluoro-4 min -O-sulfonylkanamycin B with a metal halide, reducing the resulting 4 min -halogenated 3 min -deoxy-3 min -fluorokanamycin B derivative to convert its 4 min -halo group into a hydrogen atom, and thereby to produce an N,O-protected derivative of 3 min ,4 min -dideoxy-3 min -fluorokanamycin B and removing the remaining amino-protecting groups and the remaining hydroxyl-protecting groups from the reduction product by conventional deprotecting methods.</p> |
