PREPARATION METHOD OF PYRAZOLINE DERIVATIVES

摘要

Pyrazolines I[R1=H, alkyl, Ph, cyanoalkyl or alkoxyalkyl; R2, R3=H, alkyl, Ph; R4=H or alkyl; X=H or halogen; W=O or S; Y,Z=H, halogen, alkyl, alkoxy, NO2, CF3, alkylthio, acyl, CN, alkylsulphonyl, alkoxycarbonyl or haloalkyl-A' or Y+Z form OCH2O; A'=O,S,SO or SO2) are prepd.. Thus, 4-HOC6H4COCH2Ph is treated with ClCHF2 to give 4- CF2OC6H4COCH2Ph which is treated with CH2O to give 4-CF2HOC6H4CO Ph; CH2. The latter is cyclized with N2H4 to give 3-(4- difluoromethoxyphenyl)-4-phenyl-2-pyrazoline which is treated with 4- ClC6H4NCO to give I(X=R2=R4=H, R1=Ph, W=O). (I) are broad-spectrum insecticides and are active against both young and old larvae.