| 发明名称 |
New biosynthetic anthracyclines related to daunorubicin. |
| 摘要 |
<p><CHEM> are prepared by a biosynthetic process based on the addition of sodium salt of 1,3-N,N-dimethylbarbituric acid and 2-thiobarbituric acid respectively during the fermentation process of different micro-organisms such as Streptomyces peucetius and its mutants. The novel compounds are provided with good antibacterial and antitumour activity.</p> |
| 申请公布号 |
EP0239774(A1) |
申请公布日期 |
1987.10.07 |
| 申请号 |
EP19870102446 |
申请日期 |
1987.02.20 |
| 申请人 |
FARMITALIA CARLO ERBA S.P.A. |
发明人 |
CASSINELLI, GIUSEPPE;GREIN, ARPAD;MERLI, SERGIO;RIVOLA, GIOVANNI |
| 分类号 |
C07D498/04;A61K31/65;A61K31/70;A61K31/7028;A61K31/7034;A61K31/704;A61P31/04;A61P35/00;C07H15/252;C12P19/54;C12P19/56;C12R1/465;(IPC1-7):C07H15/252 |
主分类号 |
C07D498/04 |
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