发明名称 ANTIDOTE FOR ORAL ADMINISTRATION
摘要 PURPOSE:To provide a peroral antidote containing an NH3-treated spherical activated carbon having specific particle diameter, surface area, pore volume and pH as an active component, free from side effect of constipation and exhibiting excellent antidotal effect. CONSTITUTION:An activated carbon of minute spherical form having a diameter of 0.05-2mm, a surface area of 500-2,000m<2>/g a pore volume of 0.05-1ml/g corresponding to pore radius of 100-75,000Angstrom and pH of 8-10 is produced e.g. by forming small spheres of pitch in molten state, oxidizing and infusibilizing the spherical pitch, carbonizing in an inert atmosphere at 800-1,000 deg.C and activating in steam atmosphere at 900-1,000 deg.C. The produced activated carbon is made to contact with an aqueous solution of NH3 and dried to obtain activated carbon having 6-8pH and the same shape as above. >=85% of the obtained activated carbon has true spherical form wherein the ratio of the maximum diameter and the minimum diameter is 1-1.3. A particular surface can be obtained by the NH3-treatment to acquire excellent adsorptivity compared with a conventional activated carbon.
申请公布号 JPS62223125(A) 申请公布日期 1987.10.01
申请号 JP19870012799 申请日期 1987.01.22
申请人 KUREHA CHEM IND CO LTD 发明人 NISHIMURA YASUSHI
分类号 A61K33/44;A61K9/16;A61K9/18;A61M1/36;A61P39/02;C01B31/14 主分类号 A61K33/44
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