发明名称 Thio:phenyl-methyl-phenoxy-methyl morpholine deriv. prepn.
摘要 The morpholine derivs. of formula (I), in which R1 and R2 are H, or 1-4C alkyl and their acceptable salts, for use as anti-hypoxic and anti-amnesic agents are made by (a) reacting a cpd. of formula (II) with R2NHCH2CH2Y, in which Y is halogen, in water in presence of Ba(OH)z at b.pt.; and (b) cyclising the prod. of formula (IV) at high temp. in presence of Ba(OH)2.
申请公布号 ES8707230(A3) 申请公布日期 1987.10.01
申请号 ES19800005564 申请日期 1986.06.23
申请人 YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. 发明人
分类号 A61K31/38;A61K31/535;C07D409/10;C07D413/10;(IPC1-7):C07D409/10 主分类号 A61K31/38
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