发明名称 |
Improved spray dried lactose and process for preparing the same. |
摘要 |
<p>The invention relates to a spray dried lactose suitable for use as component of tablets and to a process for preparing same. The lactose is predominantly crystalline and contains at most 50% by weight of amorphous lactose. At least 50% by weight of the crystalline lactose consists of particles below 50 mu m. The preparation process comprises a step of suspending crystalline alpha-lactose hydrate at 0-90 DEG C in a saturated lactose solution, and a spray drying step. The temperature of the suspension is kept substantially constant until the timeof spraydrying in order to minimize crystallization and dissolution events.</p> |
申请公布号 |
EP0239172(A2) |
申请公布日期 |
1987.09.30 |
申请号 |
EP19870200524 |
申请日期 |
1987.03.20 |
申请人 |
DMV-CAMPINA B.V. |
发明人 |
KUSSENDRAGER, KLAAS DANIEL;VAN DEN BIGGELAAR, HENRICUS ALPHONSUS MARIA;VROMANS, HERMAN |
分类号 |
C07H3/04;A61K9/20;C13K5/00;(IPC1-7):C13K5/00 |
主分类号 |
C07H3/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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