| 摘要 |
NEW MATERIAL:The compound of formula labeled with <99m>Tc. USE:A diagnostic agent for nephrourinary tract. It rapidly dissipates from blood, has high renal selectivity and reduces the exposure of a subject to radiation. PREPARATION:For example, nitrilotriacetic acid is made to react with acetic anhydride in a solvent such as pyridine at 100 deg.C for 30min, allowed to cool, added with N-(4-aminobenzoyl)-L-glutamic acid and reacted at 100 deg.C for 1-2hr. The resultant compound of formula is added with a solution of a pertechnetic acid in the presence of tin chloride.
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