发明名称 |
Antihypertensive phosphate derivatives |
摘要 |
Antihypertensive phosphate derivatives having the following formula are described: <IMAGE> FORMULA 1 wherein X is selected from the group consisting of a phenyl radical substituted at any position with a C1-C20 branched or straight chain alkoxy or benzyloxy and optionally substituted by any other positions with one or more groups consisting of C1-C15 branched or straight chain alkyl, C1-C15 branched or straight chain alkoxy and halogen, and a naphthalene radical substituted at any position with a C1-C20 branched or straight chain alkoxy or benzyloxy and optionally substituted at any other positions with one or more groups consisting of C1-C15 branched or straight chain alkyl, C1-C15 branched or straight chain alkoxy and halogen; T is selected from the group consisting of hydrogen and <IMAGE> wherein R1 is selected from the group consisting of hydrogen, C1-C4 branched or straight chain alkyl, C1-C4 branched or straight chain alkoxy and C1-C4 branched or straight chain alkylamino; Y is selected from the group of bivalent radicals consisting of -(CH2)p- and -(CHR)p-, wherein p is an integer from 2 to 10 and the moiety -(CHR)p- represents an alkylene chain substituted with one or more C1-C8 alkyl groups or phenyl groups; Z is selected from the group consisting of -N+(R2)3 and <IMAGE> wherein q is an integer from 4-7 and R2 may be the same or different and is selected from the group consisting of hydrogen and C1-C4 branched or straight chain alkyl.
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申请公布号 |
US4697031(A) |
申请公布日期 |
1987.09.29 |
申请号 |
US19840679792 |
申请日期 |
1984.12.10 |
申请人 |
AMERICAN CYANAMID COMPANY |
发明人 |
WISSNER, ALLAN;SUM, PHAIK-ENG |
分类号 |
C07F9/10;(IPC1-7):C07F9/10 |
主分类号 |
C07F9/10 |
代理机构 |
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地址 |
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