PLATINUM OR PALLADIUM COMPLEXES

摘要

Compositions of matter are provided wherein cis-platinum (II) and cispalladium (II) moieties having amine substituents are bonded to anionic macromolecular entities. These compositions of matter may have improved solubility inthe plasma and are effective antitrypanosomal and antitumor agents in mammals. Alternatively, the compositions of matter may be insoluble in water and particu-larly adapted for in situ implantation into tumerous masses.