Ocular antihypertensive composition for topical use.

摘要

An ocular antihypertensive composition for topical use which contains an effective amount of a compound represented by the formula
<Chemistry id="chema01" num="0001"><Image id="ia01" he="38" wi="113" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" /></Chemistry> or a salt thereof has, in low concentrations, intraocular pressure lowering activity in mammals, is low toxicity and has no influence on the pupil size and, therefore, is useful as a therapeutic agent for glaucoma, for instance.

Furthermore, since the compound is effective in low concentrations, the possibility of tolerance development therefor is considered to be scarce.