| 摘要 |
1,2,3,4-Tetrahydro-4-quinolinones of the formula <IMAGE> (I) are prepared from a 3-anilinopropionic acid of general for formula <IMAGE> (II) which is treated successively with phosgene, with a base or by heating, and then with a Lewis acid or a strong acid. In the formulae (I) and (II), R denotes a hydrogen atom, a halogen atom, an alkyl radical (1 to 4 carbon atoms) or an alkoxy radical (1 to 4 carbon atoms), and R1 denotes a hydrogen atom or any alkyl radical (1 to 4 carbon atoms). The compounds of formula I are useful as intermediates in the production of known drugs. |
