| 摘要 |
New indolizine derivatives of general formula: <IMAGE> in which: - B denotes an -S-, -SO- or -SO2- group, - R denotes hydrogen, an alkyl, a cycloalkyl or a phenyl, - each of R1 and R2, which are identical or different, denotes hydrogen, methyl, ethyl or halogen, - A denotes an alkylene or a 2-hydroxypropylene, - R3 denotes an alkyl or a radical of formula -Alk-R5 in which Alk denotes a single bond or an alkylene radical, R5 denotes a pyridine, phenyl, 2,3-methylenedioxyphenyl or 3,4-methylenedioxyphenyl radical or a phenyl group, - R4 denotes hydrogen or an alkyl, - or R3 and R4, when taken together, denote an alkylene or alkenylene radical. Application: treatment of certain pathological syndromes of the cardiovascular system. |
