| 发明名称 |
Antihypercholesterolemic compounds. |
| 摘要 |
<p>Novel 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors which are useful as antihypercholesterolemic agents and are represented by the following general structural formulae (I) and (II):
<Chemistry id="chema01" num="0001"><Image id="ia01" he="52" wi="86" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>and pharmaceutically acceptable salts of the compounds (II) in which Z is hydrogen are disclosed.</p> |
| 申请公布号 |
EP0232997(A1) |
申请公布日期 |
1987.08.19 |
| 申请号 |
EP19870300544 |
申请日期 |
1987.01.22 |
| 申请人 |
MERCK & CO. INC. |
发明人 |
SMITH, ROBERT L.;STOKKER, GERALD E. |
| 分类号 |
C07C59/48;A61K31/19;A61K31/215;A61K31/22;A61K31/365;A61P3/06;C07C51/00;C07C51/09;C07C59/56;C07C67/00;C07C69/732;C07C213/00;C07C219/10;C07C233/18;C07D309/30;(IPC1-7):C07D309/30;C07C69/76;A61K31/35 |
主分类号 |
C07C59/48 |
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