发明名称 PROCESS FOR PREPARING ALPHA-HYDROXY CARBONYL COMPOUNDS
摘要 PCT No. PCT/CH86/00157 Sec. 371 Date Jul. 16, 1987 Sec. 102(e) Date Jul. 16, 1987 PCT Filed Nov. 13, 1986 PCT Pub. No. WO87/03287 PCT Pub. Date Jun. 4, 1987.The invention is concerned with a novel process for the manufacture of compounds of the formula <IMAGE> I wherein R1 signifies C1-5-alkyl, especially methyl, ethyl, propyl or isopropyl, and the radicals R2 each independently represent hydrogen or C1-5-alkyl, especially hydrogen or methyl, ethyl, propyl or isopropyl. The process is characterized in that a compound of the formula <IMAGE> II wherein R stands for C1-4-alkoxy, chlorine, bromine or C1-4-alkanoyloxy, R1 and R2 have the above significance and R3 represents C1-4-alkyl. is hydrolyzed and subjected to an aldol condensation and, where R=C1-4-alkoxy, the reaction product is subsequently subjected to an acid treatment. The compounds I are for the most part known flavoring substances.
申请公布号 WO8703287(A3) 申请公布日期 1987.08.13
申请号 WO1986CH00157 申请日期 1986.11.13
申请人 L. GIVAUDAN & CIE SOCIETE ANONYME;WILD, HANS-JAKOB 发明人 WILD, HANS-JAKOB
分类号 C07C69/738;A61K8/35;A61Q13/00;C07C45/00;C07C45/48;C07C45/64;C07C45/66;C07C45/67;C07C49/707;C07C49/753;C07C67/00;C07C67/343;C11B9/00 主分类号 C07C69/738
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