| 摘要 |
NEW MATERIAL:The compound of formula I [X1 is H or (substituted) 1-3C alkyl; X2 is (substituted) 1-3C alkyl, (substituted) 1-2C alkylcarbonyl (1-2C alkyl), (substituted) phenyl (1-2C alkyl), etc.; X3 and X4 are H or methyl; X4 is H when X3 is methyl; X5 is H, OH or amino; X6 is H or OH; X6 is H when X5 is OH or amino; X7 is H or amino; X8 is H or H OH; X8 is H when X7 is amino; Q is (substituted) 1-11C alkyl, (substituted) 2-11C alkenyl, etc. EXAMPLE:Exo-type 6-O-(3-methyl-n-butyryl)-3',4'-O-benzylidene-4'-epiamino-4''- deoxychartreusin hydrochloride. USE:Carcinostatic agent. PREPARATION:The compound of formula II (X5' is H, OH, azido, etc.; X7' is H, azido, etc.) is made to react with the carboxylic acid derivative of formula III.
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