3-diphenyl substituted octahydroindolizine analgesic compounds

摘要

Octahydroindolizine compounds of formula (I): <IMAGE> (I) wherein Q is -NR-, -(CH2)z-, -CH=CH-, -C 3BOND C-, -OCH2-, -SCH2-, -SO2-, -SO-, -CO-, or an oxygen or a sulfur atom and where R, R1 and R2 are substituents such as alkyl and x, y and z are independently the integers 0-3. Also, pharmaceutical compositions containing (I), intermediates and methods for treating pain.