| 摘要 |
PURPOSE:A substituent is introduced into L-gamma-glutamylanilide to give a substrate for determining gamma-glutamyl-transpeptidase with good solubility such as a carboxyanilide. CONSTITUTION:A substituent is introduced into L-gamma-glutamylanilide, for example, L-gamma-glutamylanilide bearing carboxyl and hydroxyl introduced or glycine is introduced into L-gamma-glutamyl-4-carboxyanilide through an amide linkage. The resultant novel compounds are, etc., L-gamma-alutamyl-3-hydroxyl-4-carboxyanilide or L-gamma-glutamyl-4-carboxyglycinamidanilide (formula I, formula II). The compound have high solubility and is suitable for use as a substrate for determination of gamma-glutamyl-transpeptidase.
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