| 摘要 |
NEW MATERIAL:The compound of formula I [R<1> is (protected) amino; R<3> is H or (substituted) hydrocarbon residue; Z is S, S O, O or CH2; R<4> is H, methoxy or formamide; R<13> is H, methyl, OH or halogen A<+> is (substituted) imidazolium-1-yl which forms a condensed ring at 2,3- or 3,4-sites], its salt or ester. EXAMPLE:7beta-[2-( 5-Amino-1, 2,4-thiadiazol-3-yl )-2(Z)-ethoximinoacetamido]-3-[(6- cyanoimidazo[1,2-a]pyridinium-1-yl)methyl]-3-cephem-4-carboxylate. USE:Antibacterial agent. PREPARATION:The compound of formula II or its salt or ester is made to react with the carboxylic acid of formula III or its salt or reactive derivative. |
