| 摘要 |
The rate of absorption of a physiologically active agent across skin and body membranes of animals and humans is incresed by adding to a composition containing the active agent a lactone or a cyclic ketone of formula (I) or a cyclic anhydride or ester of formula (II), wherein m+n are integers having a value from 1 to 20 with the proviso that m+n is at least 11 and not greater than 25, p is an integer having a value of 0 or 1, q is an integer having a value of 0 or 1, and R is hydrogen or an alkyl group having from 1 to 6 carbon atoms. And as for a cyclic anhydride or ester, x is an integer having a value of 0 or 1 to 20, y is an integer having a value of 0 or 1 and z is an integer having a value of 0 or 1. |
