摘要 |
A compound of the general formula I: <IMAGE> (I) or a salt or solvate thereof, in which, R1 represents hydrogen or a lower alkyl group, R2 represents hydrogen, a lower alkyl group, or <IMAGE> R3 represents hydrogen, a lower alkyl group, or <IMAGE> R4 represents a lower alkyl group substituted by one or more fluorine atoms, R5 represents hydrogen, halogen or lower alkyl, and R6 represents a lower alkyl or a substituted or unsubstituted carbocyclic aryl group. The compounds are useful as inhibitors of 5-lipoxygenase. |