发明名称 DERIVATIVES OF 2-FLUOROALKYLBENZIMIDAZOLE,PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
摘要 A compound of the general formula I: <IMAGE> (I) or a salt or solvate thereof, in which, R1 represents hydrogen or a lower alkyl group, R2 represents hydrogen, a lower alkyl group, or <IMAGE> R3 represents hydrogen, a lower alkyl group, or <IMAGE> R4 represents a lower alkyl group substituted by one or more fluorine atoms, R5 represents hydrogen, halogen or lower alkyl, and R6 represents a lower alkyl or a substituted or unsubstituted carbocyclic aryl group. The compounds are useful as inhibitors of 5-lipoxygenase.
申请公布号 ZA8604504(B) 申请公布日期 1987.06.24
申请号 ZA19860004504 申请日期 1986.06.17
申请人 BEECHAM GROUP PLC 发明人 ROGER EDWARD MARKWELL;STEPHEN ALLAN SMITH
分类号 A61K31/415;A61K31/4184;A61P1/04;A61P11/00;A61P27/16;A61P29/00;A61P37/08;C07D235/10 主分类号 A61K31/415
代理机构 代理人
主权项
地址