FORFARANDE FOR FRAMSTELLNING AV N-/2-//5-/(DIMETYLAMINO) METYL/-2-FURANYLMETYL/-TIO/ETYL/N'-METYL-2-NITRO-1,1-ETENDIAMIN (RANITIDIN)

摘要

The invention relates to a process for the preparation of ranitidine of the formula: which is characterised in that a thiol of the formula: is reacted with an alkylating agent of the formula: in which R1 denotes the group -CH2CH2L, where L represents a leaving group, and R2 represents a hydrogen atom or R1 and R2, together with the nitrogen atom to which they are attached, form an ethyleneimino group.