| 发明名称 |
PROCESS FOR THE PREPARATION OF 1-HYDROXYLATED VITAMIN D COMPOUNDS |
| 摘要 |
<p>"Process for the preparation of 1-hydroxylated Vitamin D compounds" 1-unsubstituted 5,6-trans vitamin D compounds are 1.alpha.-hydroxylated by SeIV oxidation in the presence of selenous acid at a pH in the range 3-9. The oxidation is preferably effected using a 1-unsubstituted-3-trihydro-carbylsilyloxy-5,6-trans vitamin D compound in the presence of a co-oxidant.</p> |
| 申请公布号 |
CA1221707(A) |
申请公布日期 |
1987.05.12 |
| 申请号 |
CA19820414662 |
申请日期 |
1982.11.02 |
| 申请人 |
RESEARCH INSTITUTE FOR MEDICINE AND CHEMISTRY INC. |
发明人 |
HESSE, ROBERT H. |
| 分类号 |
C07C29/40;C07D303/04;C07D309/12;C07D487/04;C07F7/18;C07F9/53;C07F9/54;C07F9/655;(IPC1-7):C07C172/00 |
主分类号 |
C07C29/40 |
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