(6R,7R)-7-/(Z)-2-(2-AMINOTIAZOL-4-YL)-2-(2-KARBOXIPROP-2-OXIIMINO)ACETAMIDO/-3-(1-PYRIDINIUMMETYL)CEF-3-EM-4-KARBOXYLATPENTAHYDRAT, FORFARANDE FOR DESS FRAMSTELLNING OCH FARMACEUTISK KOMPOSITION DERAV

摘要

(6R,7R)-7-[(Z)-2-(2-Aminothiazol-4-yl)-2-(2-carboxyprop-2-oxyimino)ace tamido]-3-(1-pyridiniummethyl)ceph-3-em-4-carboxylate in the form of its crystalline pentahydrate. This pentahydrate has a well defined crystalline structure and exhibits good stability on storage. The pentahydrate exhibits excellent antibiotic activity, particularly against organisms which are normally difficult to combat with beta -lactam antibiotics.