发明名称 |
DEPOLYMERIZED AND SUPERSULFATED HEPARIN, PROCESS FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
摘要 |
Novel depolymerized and supersulfated heparin having a molecular weight comprised between 2000 and 9000 and a sulfation degree of at least 2.5, in which all of the primary hydroxy groups are sulfated; a process for its preparation by reacting a heparin of natural origin, or a fraction thereof with a sulfuric acid/chlorosulfonic acid mixture; and pharmaceutical compositions containing it as active ingredient, having potential antithrombotic, hypolipemic and fibrinolytic activity and useful in the prevention of thrombosis and for the treatment of atherosclerosis. |
申请公布号 |
DE3370632(D1) |
申请公布日期 |
1987.05.07 |
申请号 |
DE19833370632 |
申请日期 |
1983.12.26 |
申请人 |
SCLAVO S.P.A.;SANOFI, SOCIETE ANONYME |
发明人 |
NAGGI, ANNAMARIA;TORRI, GIANGIACOMO |
分类号 |
C08B31/06;A61K31/715;A61P3/06;A61P7/02;A61P7/04;C08B37/00;C08B37/10;(IPC1-7):C08B37/10;A61K31/725 |
主分类号 |
C08B31/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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