发明名称 FOERFARANDE FOER FRAMSTAELLNING AV NYA TERAPEUTISKT ANVAENDBARA 4H-1,2,4-TRIAZOLDERIVAT.
摘要 Novel 4H-1,2,4-triazoles of the formula <IMAGE> I wherein R1, R2, R3 and R4 may be in different positions of the benzene rings and are individually selected from the group consisting of hydrogen, -OH, alkyl of 1 to 4 carbon atoms, alkoxy of 1 to 4 carbon atoms, halogen, -CF3, -NO2, -NH2 and -NH-AlK and <IMAGE> and AlK, AlK1 and AlK2 are alkyl of 1 to 4 carbon atoms or R1 and R2 together and/or R3 and R4 together are methylenedioxy, R is selected from the group consisting hydrogen, alkyl of 1 to 4 carbon atoms, -CH2-COOH and -CH2-COOAlK3 and AlK3 is alkyl of 1 to 4 carbon atoms and their non-toxic, pharmaceutically acceptable acid addition salts having a remarkable analgesic activity and a novel method for their preparation.
申请公布号 FI72971(B) 申请公布日期 1987.04.30
申请号 FI19810002585 申请日期 1981.08.21
申请人 ROUSSEL-UCLAF 发明人 MEIER, JEAN;CLEMENCE, FRANCOIS
分类号 A61K31/41;A61P25/04;C07C243/38;C07D249/08;C07D317/46;C07D405/04 主分类号 A61K31/41
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