Antihypertensive agents comprising 2-alkynyladenosines as active ingredients.

摘要

A 2-alkynyladenosine represented by general formula [l]:
<Chemistry id="chema01" num="0001"><Image id="ia01" he="46" wi="80" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>wherein n is an integer of from 2 to 15, has been found to have excellent properties as an antihypertensive agent. On the basis of this finding, the present invention has provided an antihypertensive agent comprising an antihypertensive effective amount of a compound of the above formula [l] and a pharmaceutically acceptable carrier. The present invention also discloses a novel compound 2-alkynyladenosine of formula [l] shown above wherein n is 6 to 15.