NOVEL DERIVATIVES OF THE OLIGOSACCHARIDE ANTIBIOTIC COMPLEX 13-384, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

摘要

Novel derivatives of the oligosaccharide antibiotic complex 13-384, the derivatives being of general formula (I), wherein R is hydrogen or Z, where Z is a moiety of general formula (II) in which R1 is nitroso, N-hydroxylamino, N-acyl-N-hydroxyl-amino, N-acylamino, N-alkylamino or N,N-dialkylamino and their pharmaceutically acceptable salts. Also disclosed are processes for the preparation of the derivatives and pharmaceutical compositions containing them. The novel derivatives exhibit advantageous antibacterially properties.