Methods for isolating cell fusion products

摘要

A method for isolating the fusion product of two cell populations is disclosed. The method involves the introduction of a specific antitoxin into cells of one population while introducing a second specific antitoxin into cells of the second population. After fusing cells of the first population with those of the second population, the fusion product may be selectively isolated on a medium containing an appropriate amount of both first and second toxins. For some applications, it may be appropriate to introduce an antitoxin into only one of the cell populations and isolate the fusion product on a media containing only one toxin.