| 摘要 |
PURPOSE:To provide the titled preparation containing carboxymethylated chitin as a component, available at an extremely low cost compared with sodium hyaluronate, having high decomposability, effective to minimize the post-operative increment of intraocular tension, etc., and useful especially as a protomerite infusion for the operation of anterior chamber. CONSTITUTION:Carboxymethylated chitin (abbreviated as CM-chitin) is a water- soluble chitin produced by converting chitin to alkali chitin and reacting with a monohalogenoacetic acid salt. CM-chitin especially having a carboxymethyl- substitution degree of about 1.0-2.5 per one monosaccharide residue is effective as a protomerite infusion for the operation of anterior chamber, a remedy for arthritis or an external coating agent for urinary catheter or insertion tube of gastric camera scope. Isotonic agent can be freely selected and no viscosity lowering occurs even by dry thermal sterilization. The safety of the present agent is comparable to or higher than that of sodium hyaluronate. |
