| 摘要 |
<p>NEW MATERIAL:The compound of formula I (R<1> is carboxy, tetrazolylcarbamoyl or amino-substituted tetrazolylcarbamoyl; R<2> is H or lower alkoxy; R<3> is H, aroyl, aryl, carboxy or protected carboxy; R<4> is H or OH; when R<3> is H, R<4> is OH; when R<3> is aryl, R<1> is amino-substituted triazolylcarbamoyl; when R<3> is aroyl, R<2> is lower alkoxy) and its salt. EXAMPLE:1-Benzoyl-7-n-butoxy-N-(1H-tetrazol-5-yl)-4H-quinolizin-4-one- 3-carbox amide. USE:Remedy for allergic diseases and ulcer. PREPARATION:The compound of formula III can be produced e.g. by eliminating the carboxyl-protecting group from the compound of formula II (R<3>a is H, aroyl, carboxy or protected carboxy; R<5> is protected carboxy).</p> |
