| 摘要 |
Compounds of the formula 1 <IMAGE> in which R<1> is H, halogen, OH, SH, azido, NH2 or Z-R<5>, where Z denotes O, S, SO, SO2 or NH and R<5> denotes an acyclic aliphatic hydrocarbon radical having 1 to 6 C atoms, which a) is unsubstituted or b) is modified by at least one of the features that it contains an alkoxy group having 1 to 3 C atoms or a double bond or is at least partially fluorinated, or denotes cycloalkyl having 3 to 6 C atoms or phenylalkyl which is bonded directly to Z or via an alkylene group of 1 to 3 C atoms, or phenyl, where the phenyl ring can in each case be substituted at most twice, preferably at most once, by a substituent from the group halogen, trifluoromethyl, alkoxy and alkylthio each having 1 to 3 C atoms, R<2> is H or has the meaning of R<5> or is an acyl group CO-R<6>, where R<6> is alkyl having 1 to 6 C atoms, benzyl or phenyl, R<3> denotes halogen, azido, unsubstituted amino or the radical Y-R<4>, where R<4> has the same meaning as R<5> and Y, like X, denotes O, S, SO or SO2 and X and Y can be identical or different, where those compounds are excepted in which, at the same time, R<1> is OH or SH, R<2> is H, R<3> is Y-R<4>, X is O or S, Y is O and R<4> is alkyl having 1 to 4 C atoms or in which, at the same time, R<1> is OH or NH2, R<2> is benzyl, R<3> is Y-R<4> where Y = O and R<4> = benzyl and X is O, are used for the treatment of diseases caused by viruses. |
