| 摘要 |
6-(4-(1-Cyclohexyl 5-tetrazolyl)butoxy)1,2,3,4-tetrahydro 2-oxo quinoline of formula (I), for use as a platelet anti-aggregant and anti-thrombosis agent with peripheral vaso-dilatory effect, is made by reacting 6-(4-(5-tetrazolyl)butoxy 1,2,3,4-tetrahydro 2-oxo quinoline with a cyclohexyl halide in presence of an alkali hydride e.g. sodium hydride in aromatic hydrocarbon e.g. toluene at ambient temp up to b.pt., for 1-24 hrs.
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