发明名称 Enhanced absorption of psychoactive 2-aryl-pyrazolo quinolines as a solid molecular dispersion in polyvinylpyrrolidone.
摘要 The absorption of orally administered substantially aqueous insoluble psychoactive 2-aryl-pyrazolo [4,3-C] quinolin-3-ones of the formula <CHEM> wherein R sec is hydrogen, lower alkyl, lower alkoxy, hydroxy, halo or trifluoromethyl, and R min is hydrogen, lower alkyl, lower alkoxy, hydroxy, halo, trifluoromethyl, nitro, amino, mono- or di-lower alkylamino, mono- or di-lower alkylcarbamoylamino, mono- or di-lower alkylcarbamoyloxy or cyano, or a pharmaceutically acceptable salt thereof, is enhanced by administering the same in the form of a storage stable solid molecular dispersion of polyvinylpyrrolidone.
申请公布号 EP0214092(A1) 申请公布日期 1987.03.11
申请号 EP19860810342 申请日期 1986.08.01
申请人 CIBA-GEIGY AG 发明人 LEESON, LEWIS, J.
分类号 A61K31/435;A61K9/14;A61K31/47;A61K47/32;A61P25/24;A61P25/26;(IPC1-7):A61K31/47;A61K47/00 主分类号 A61K31/435
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