| 摘要 |
PURPOSE:The titled gel ointment, obtained by incorporating a vidarabin with a local anesthesia, carboxyvinyl polymer which is a viscosity increasing agent, lower alcohol, neutralizing agent and water in a specific proprtion, readily handleable and having improved feeling of use, drug effect on herpes zoster, etc. CONSTITUTION:A vidarabin gel ointment obtained by incorporating 0.05-1wt% (expressed in terms of vidarabin) vidarabin expressed by the formula with 0-10wt% local anethesia, 0.1-5wt% carboxyvinyl polymer, 5-30wt% wetting agent, e.g. PEG, 5-50wt% 1-3C lower alcohol, neutralizing agent for adjusting pH and water in an adequate amount. The ointment is characterized in that the carboxyvinyl polymer is used as the gelling and viscosity increasing agent. The oingment has more improved feeling of use and percutaneous absorbability than the conventional oily ointment, and can be effectively used for local diseases, e.g. herpes zoster, labial herpes, etc., with good storage stability. |
